Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation.
AZ2; AZ2 ODC-Az 2; ODC-Az 2; Ornithine decarboxylase antizyme 2
Cat # 15749381
100 µL
Cat # 15833154
100 µL
Cat # 16620445
100 µL
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