OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2′,5′-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP(A2′P5′A)N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
(2-5')oligo(A) synthase 3; (2-5')oligo(A) synthetase 3; 2'-5'-oligoadenylate synthase 3; 2'-5'-oligoadenylate synthetase 3, 100kDa; 2'-5'oligoadenylate synthetase p100; 2-5A synthase 3; 2-5A synthetase 3; p100 (2-5&prime)oligo(A) synthase 3 (2-5&prime)oligo(A) synthetase 3 2&prime-5&prime-oligoadenylate synthase 3 2&prime-5&primeoligoadenylate synthetase p100 2-5A synthase 3 2-5A synthetase 3 p100 OAS p100OAS; p100 OAS; p100OAS
Cat # 15737351
100 µL
Cat # 16116200
100 uL
Cat # 16530052
100 µL
Cat # 16821465
150 µL
Cat # 16196210
100 uL
Cat # 15777391
100 µL
Cat # 16831465
20 µL
Cat # 13425607
100 µL
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