This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2′-specific nucleotidyl transfer reactions to synthesize 2′,5′-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
(2'-5')oligo(A) synthetase 2; (2-5')oligo(A) synthase 2; 2&prime-5&prime-oligoadenylate synthetase 2 69/71kDa 2&prime-5&primeoligo A synthetase 2 2&prime-5&prime-oligoadenylate synthase 2 2-5A synthase 2 p69 OAS / p71 OAS; 2'-5'-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS
Cat # 15936154
100 µL
Cat # 16888944
150 µL
Cat # 15584811
100 µg
Cat # 16892744
20 µL
Cat # 15714694
25 ug
Cat # 16898944
20 µL
Cat # 15674175
100 µL
Cat # 15594811
100 µg
Cat # 15928174
100 µL
Cat # 17258463
100 µL
Cat # 17177983
100 µL
Cat # 15796056
0.1 ml
Cat # 15986144
100 µL
Cat # 13439035
100 ug
Cat # 16882744
150 µL
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