The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer′s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
amyloid beta precursor protein binding protein 1, 59kDa; Amyloid beta precursor protein-binding protein 1, 59 kDa; amyloid beta precursor protein-binding protein 1, 59kD; Amyloid protein-binding protein 1; APP-BP1; HPP1 ula-1 NAE1 A-116A10.1 NEDD8-activating enzyme E1 regulatory subunit Amyloid protein-binding protein 1Amyloid beta precursor protein-binding protein 1 59 kDa Proto-oncogene protein 1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8-activating enzyme E1 subunit; Proto-oncogene protein 1; protooncogene protein 1
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400 uL
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100 ug
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200 uL
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50 ug
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100 µg
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100 µg
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