NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
GTPase NRas; N-RAS Neuroblastoma RAS NRAS NRAS1 NS6 ALPS4 Neuroblastoma RAS viral (v-ras) oncogene homolog RAS RASN GTPase Nras Transforming protein N-Ras; N-ras protein part 4; neuroblastoma RAS viral (v-ras) oncogene homolog; Transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
Cat # 10819010
400 µL
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100 µL
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100 µL
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400 µL
Cat # 11366863
100 µg
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100 µL
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100 µg
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100 µg
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