Human ether-a-go-go related gene (HERG) encodes the pore-forming alpha subunit of the delayed rectifier potassium channel IKr. There are two N-terminal splice variants of HERG include the full-length isoform 1 alpha and the shorter isoform 1 beta. Isoform 1 beta lacks the PAS motif and deactivates at a faster rate than isoform 1alpha. Residues within the C-terminal play a role in channel expression and channel gating, including voltage-dependent activation. HERG is expressed in the heart and is more abundantly expressed in the ventricles than in the atria. Mutations in the gene encoding HERG increase beat-to-beat ...
Cat # 15807083
100 µL
Cat # 11578851
100 µL
Cat # 15964115
50 µL
Cat # 15974085
50 µL
Cat # 15372781
50 µg
Cat # 16007747
50 ug
Cat # 16017747
50 ug
Cat # 15362781
50 µg
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