JHDM1D histone demethylase that specifically demethylates dimethylated ′Lys-9′ and ′Lys-27′ (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated ′Lys-4′ of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3.
histone lysine demethylase JHDM1D; JmjC domain-containing histone demethylation protein 1D; jumonji C domain containing histone demethylase 1 homolog D; jumonji C domain-containing histone demethylase 1 homolog D; KDM7A histone lysine demethylase JHDM1D jmjC domain-containing histone demethylation protein 1D jumonji C domain-containing histone demethylase 1 homolog D lysine-specific demethylase 7; lysine (K)-specific demethylase 7A; Lysine-specific demethylase 7; Lysine-specific demethylase 7A
Cat # 13272659
400 µL
Cat # 15952885
100 µL
Cat # 15750861
100 µL
Cat # 16549821
100 µL
Cat # 16123650
100 uL
Cat # 16507641
100 µL
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