GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.
6330404F12Rik antibody GAD(65) antibody GAD65 antibody GAD65 antibody Gad2 antibody glutamic acid decarboxylase 2 antibody; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 2; Glutamate decarboxylase 2 (islet); glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); glutamic acid decarboxylase 2; glutamic acid decarboxylase 65
Cat # 16302685
100 µL
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100 µg
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100 µg
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20 µL
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100 µL
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150 µL
Cat # 15944865
100 µg
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100 µL
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100 µL
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20 µL
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100 µL
Cat # 11336343
100 µg
Cat # 16326694
100 µl
Cat # 16840315
150 µL
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