This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E , which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
4E-BP1; 4EBP1 4E-BP1 AA959816 BP-1 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 MGC431 MGC4316 P/OKCL.6 PHAS-1 PHAS-I Phosphorylated heat- and acid-stable protein regulated by insulin 1; eIF4E-binding protein 1; Eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Cat # 17137143
100 µL
Cat # 11556990
100 µL
Cat # 16817285
150 µL
Cat # 11325293
100 µL
Cat # 12838302
100 µg
Cat # 11564971
100 µL
Cat # 16379794
100 µL
Cat # 16315894
100 µL
Cat # 11315293
100 µL
Cat # 11335293
100 µg
Cat # 10037712
100 µg
Cat # 10587240
400 µL
Cat # 13498044
100 ug
Cat # 13443067
100 µL
Cat # 13445177
100 µL
Cat # 15701914
25 ug
Cat # 16303485
100 µL
Cat # 17105893
100 µL
Cat # 16827285
20 µL
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